後退

講師

食品及健康科學學系

聯絡方法

電郵: chenjy06@thei.edu.hk

電話: +852 3890 8512

Qualifications

• Doctor of Philosophy in Biology, The Hong Kong Polytechnic University
• Master of Science in Food Safety and Toxicology, The University of Hong Kong
• Bachelor of Engineering in Viticulture and Enology, Northwest A&F University ，Xi’an, China

June 2026-present

Lecturer, Department of Food and Health Sciences, Technological and Higher Education Institute of Hong Kong (THEi)

April 2026-May 2026

BD director, Medical & Clinical Division, Institute of TCM in China Resources Sanjiu

June 2023- April 2026

Postdoctoral Research Fellow, Applied Biology and Chemical Technology, The Hong Kong Polytechnic University

  1. General Biology
  2.  Infection Control

Mechanisms of bioactive compounds in cancer therapy

  1. Chen J, Gao S, Zhang X, Li N, Yu Y, Wang L, Feng Y, Lao Y, Zhao Y. Autophagy-Targeting Stapled Peptide Utilizes Macropinocytosis for Cell Entry to Potentiate Anti-Proliferative Autosis in Small-Cell Lung Cancer. (2025) Pharmaceutics. 17(12):1521.
  2. Li N, Li X, Qiu X, Pan X, Wu S, Chen J, Liu R, Lu J, Yue Z, Zhao Y. (2025) “NRBF2 homodimerization by its coiled coil domain strengthens association with the PtdIns3K complex mediated by the MIT domain to promote autophagy”Autophagy. 22(1):168-181.
  3. Gao S, Li N, Zhang X, Chen J, Ko BCB, Zhao Y. (2023). “An autophagy inducing stapled peptide promotes c-MET degradation and overrides adaptive resistance to sorafenib in c-MET+ hepatocellular carcinoma.” Biochemistry and Biophysics Reports 33: 101412.
  4. Li N, Zhang X, Chen J, Gao S, Wang L, Zhao Y. (2023). “Perturbation of Autophagy by a Beclin 1-Targeting Stapled Peptide Induces Mitochondria Stress and Inhibits Proliferation of Pancreatic Cancer Cells.” Cancers 15(3): 953.
  5. Zhang X, Shan G, Li N, Chen J, Ji C, Li X, Jiang L, Lee TKW, Keng VW, Zhao Y. (2023) “An autophagy-inducing stapled peptide induces mitochondria dysfunction and triggers autotic cell death in triple-negative breast cancer.” Cell Death Discov. 9(1):303.
  6. Chen J, Zhang X, Gao S, Li N, Keng V, Zhao Y. (2022). “A Beclin 1- targeting stapled peptide synergizes with erlotinib to potently inhibit proliferation of non-small cell lung cancer cells.” Biochemical and Biophysical Research Communications 636: 125-131.