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Department of Food and Health Sciences

Academic Staff

TEACHING AREAS

  • 功能性食品和營養保健品
  • 微生物檢測的檢測和認證
  • 食品毒理學
  • 人體生理學
  • 中醫
  • 藥理學
  • 生物統計學

EMPLOYMENT

2017 - 至今 香港高等教育科技學院食物及健康科學系主任,青衣,香港
2016 - 至今 香港科技及高等教育學院(香港青衣)食品科學與安全(榮譽)理學士及1)測試及認證(榮譽)理學士副教授及課程負責人
2014 - 2016 香港青衣香港科技及高等教育學院食品科學與安全理學士助理教授兼課程負責人
2012 - 2014 香港理工大學應用生物及化學科技學系食物安全及科技研究中心助理主任。
2012 - 2014 中藥與分子藥理學國家重點實驗室主任助理,中國深圳。
2005 - 2014 香港理工大學應用生物及化學科技學系講師、助學士。
2008 - 2012 中藥與分子藥理學國家重點實驗室藥理學科科學顧問,中國深圳
2002 - 2006 香港理工大學學生事務處客座講師(兼職)。

VISITING APPOINTMENTS

2017 - 至今 香港理工大學應用生物及化學科技學系客座副教授
2014 - 至今 香港理工大學應用生物及化學科技學系食物安全及科技研究中心助理主任
2014 - 2017 香港理工大學應用生物及化學科技學系客座助理教授
2014 - 2017 副主任,中藥與分子藥理學國家重點實驗室,中國深圳

PROFESSIONAL SOCIETIES AND AFFILIATION

2014 - 至今 香港Q唛標誌委員會技術專家,香港
2012 - 2015 香港食品科技協會內部副主席
2010 - 2012 香港食品科技協會會員

AWARDS

2007 - 2008 香港理工大學應用生物及化學科技學系傑出表現員工獎。
2001 - 2002 香港理工大學應用生物及化學科技學系傑出表現員工獎。

RESEARCH EXPERIENCE

以下期刊編委

RESEARCH INTERESTS

  • 功能性食品和神經保健品
  • 食品安全
  • 心血管生理學
  • 中醫
  • 藥理學
  • 食品微生物學

SELECTED PUBLICATION

研究論文

發表在SCI期刊上的論文

  • 吳旭, 陳偉文, 馬傑, 李平, 邵平, 林國. (2018) 化學特徵與各種荸薺屬中藥材貝木氣管支氣管鬆弛活性的關聯性研究.民族藥理學雜誌。210: 39-46.
  • Li S, Ai N, Shen M, Dang Y, Chong CM, Pan P, Kwan YW, Chan SW, Leung GPH, Hoi MPM, Hou T, Lee SM. (2017) 發現一種ROCK抑製劑FPND,該抑製劑通過干擾VE-鈣粘蛋白來維持血管完整性來預防腦出血。細胞死亡發現。3: 17051.
  • Chan JY, Zhou H, Kwan YW, Chan SW, Radis-Baptista G, Lee SM. (2017) 斑馬魚模型中羅丹明B-綴合巴豆胺毒性的評估,羅丹明B-綴合的巴豆胺是一種可能對診斷和治療有用的肽。生化與分子毒理學雜誌.31(11):e21964。
  • 高麗, 蕭美, 陳偉文, 黎文建.(2017) 丹參酸A對同型半胱氨酸水準升高的db / db小鼠的心血管保護作用。氧化醫學和細胞壽命。2017: 9506925.
  • 張華, 周新, 黃敏軒, 文慶, 品偉強, 楊建柱, 關玉華, 梁家輝, 許美, 李思慧, 陳婷婷, 莫大偉偉, 余鳳峰, 陳偉*.(2017) 四川辣椒衰減H2O2-通過抗氧化活性和上調原代大鼠肝細胞中的血紅素加氧酶-1基因表達誘導細胞凋亡。食品生物化學雜誌.(已接受)。
  • 張華, 吳敏, 郭德, 萬春波, 陳偉*.(2017)桂玲高通過抑制分離的小鼠脾細胞中iNOS和促炎細胞因數的表達來抑制刀豆球蛋白A誘導的炎症。食品生物化學雜誌.41:e12367。
  • 林文, 王茹, 陳炳, 陳偉文, 曾玉峰, 蔡華, 於鳳凰.(2017) 利用不同廢水處理工藝的污泥生產聚羥基鏈烷酸酯(PHA)以及醫療和製藥應用的潛力。環境技術。38(13-14): 1779-1791.
  • 沈天文, 李敏, 陳玲, 張華, 陳偉文, 莫大.(2017)使用非靶向代謝組學的皮西坦醇(一種來自葡萄酒的二苯乙烯)的降膽固醇作用。功能性食品雜誌。28: 127-137.
  • 周旭, 崔剛, 曾華華, 李思明, 梁家輝, 陳偉偉, 關耀, 海議員.(2016) 血管對認知障礙的貢獻和中醫治療.循證補充和替代醫學。2016: 9627258.
  • 周旭, 崔淑賢, 楊建, 或PMY, 海美, 李思明, 梁家輝, 魏思敏, 孔斯, 何海, 黃敏, 陳偉*, 楊建港, 關玉偉.(2016) 多種提取方法製備黃芩(黃芩)提取物的化學和藥理評價.斯普林格加。5: 1438.
  • 梁文林, 潘英, 程海, 李天昌, 於鳳凰, 陳文*.(2016) 香港銷售的外賣生鮭魚手指壽司的微生物品質。食品控制。69: 45-50.
  • 唐炳, 楊春, 李瑞文, 李文賢, 海議員, 陳偉文, 關耀華, 謝賢, 梁國強.(2016) 4-(4-(2-氟苯基)哌嗪-1-基甲基)-6-亞氨基-N-(萘-2-基)-1,3,5-三嗪-2-胺抑制人平衡核苷轉運蛋白。歐洲藥理學雜誌。791: 544-551.
  • 高鑫, 李春, 唐彥, 張華, 陳偉*.(2016) 彌散海桔水提取物對保護人肝細胞(LO2) 從 H2O2-誘導的細胞毒性。藥物生物學。54(7): 1148-1155.
  • (2016) 來自Cimicifuga foetida(Sheng ma)的新型環素三萜類化合物通過抑制人乳腺癌MCF-7細胞中的Raf / MEK / ERK途徑和Akt磷酸化誘導線粒體凋亡。中醫。11: 1.
  • 李淑, 黨英, 周旭, 黃斌, 黃旭, 張孜, 關玉華, 陳偉文, 梁國強, 李思明, 海議員.(2015) Formononetin通過雌激素受體α增強的ROCK途徑促進血管生成。科學報告。5: 16815.
  • 潘CC, 李瑞文, 瀨戶SW, 江SK, 何海, 海議員, 李文明, 魏明, 陳偉偉, 梁家輝, 關耀.(2015)體外維生素K2和1α,25-二羥基維生素D3組合增強糖尿病小鼠成骨細胞合成代謝。歐洲藥理學雜誌。767:30-40.
  • 嚴春, 黃一, 陳建峰, 簡建偉, 張天昌, 羅明, 趙茹, 陳偉偉, 陳思, 周林.(2015)一類新的安全,有效和特異性的p-gp調節劑:類黃酮二聚體FD18逆轉體內人乳腺異種移植物中P-gp介導的多葯耐藥性。分子藥劑學。12(10): 3507-3517.
  • 崔國忠, 單立, 朱一, 李建華, 梁家輝, 王玉青, 海美, 關玉偉, 陳偉偉, 李思慧.(2015) 鑒定二硫異構酶ERp57作為小分子心臟保護劑的靶標。RSC進步。5: 74605-74610.
  • 郭玉青, 孫海, 陳科, 劉BB, 吳建華, 陳偉文, 莫丹康, 謝阿克, 於中林, 陳淑. (2015) 蜈蚣提取物抑制鼻咽癌CNE-3細胞中的PI1K-Akt-mTOR信號傳導。中醫。10: 26.
  • 楊玲, 趙春, 陳旫, 陳偉*, 吳建英.(2015) 不同方法提取杞多糖的化學性質及生物活性.功能性食品雜誌。17: 903–909.
  • 李建軍, 周淑, 林可, 於鳳凰, 李思美, 陳偉*.(2015) Fraxini (Qingpi) 保護大鼠嗜鉻細胞瘤 (PC12) 細胞免受 6-羥基多巴胺誘導的細胞凋亡。帕金森病。2015: 532849.
  • 張淑, 陳, 周旭, 陳曉, 莫大偉, 林中興, 王玉華.(2015) 亞洲人群 ALDH2 rs671 多態性與原發性高血壓之間關聯的薈萃分析。赫茲40(S2):203-208。
  • 張LQ, Sa F, Chong CM, Wang Y, Zhou ZY, Chang CC, Chan SW, Hoi PM, Yuen Lee SM. (2015) 裂藻素A通過ROS/NO和AKT/GSK6β途徑防止斑馬魚中5-OHDA誘導的多巴胺能神經元損傷和SH-SY3Y細胞的細胞毒性。民族藥理學雜誌。170: 5-15
  • 李瑞文, 楊春, 單林, 張孜, 王彥, 關耀偉, 李明, 海議員, 陳偉偉, 張建, 張康, 梁家輝.(2015) 新型丹參素/四甲基吡嗪衍生物對大鼠腸系膜動脈的鬆弛作用.歐洲藥理學雜誌。761: 153-160.
  • 李瑞文, 楊春, 陳偉文, 海議員, 李明文, 關耀, 梁家輝.(2015) 阿巴卡韋對大鼠基底動脈的鬆弛作用.公共圖書館一號。10(4):e0123043。
  • 李淑, 周興, 黨英, 關耀華, 陳偉偉, 梁家輝, 李思慧, 海美明.(2015) 基礎 Flt1 酪氨酸激酶活性是斑馬魚胚胎發生過程中內皮存活和血管形成的正向調節因數。生物化學和生物物理學報 - 一般科目。1850(2): 373-384.
  • Wu J, Liu X, Chan Co, Mok DK, Chan SW*, Yu Z, Chen S. (2014) 多花薔薇臀部的石油醚提取可改善大鼠膠原蛋白誘導的關節炎。 民族藥理學雜誌。157: 45-54.
  • 李淑, 黨耀, 車高, 關玉偉, 陳偉偉, 梁家輝, 李思慧, 海美明.(2014)VEGFR酪氨酸激酶抑製劑II(VRI)誘導斑馬魚血管功能不全作為研究血管毒性和血管保存的模型。毒理學和應用藥理學。280(3): 408-420.
  • 唐平, 吳玉峰, 何淑賢, 吉達德, 陳偉*.(2014) 白藜蘆醇與心血管健康 - 有希望的治療還是無望的幻覺?藥理學研究。90: 88-115.
  • 李岑, 郭玉青, 董曉, 李華, 王斌, 吳建華, 黃女士, 陳偉*.(2014) 川芎根莖乙醇提取物增強高脂飲食卵巢切除大鼠的內皮依賴性血管反應性。食品與功能。5(10): 2475-2485.
  • 唐玉,陳文*.(2014) 皮西坦醇對心血管疾病的藥理作用研究進展.植物療法研究。28(11): 1581-1588.
  • 陳貞婷, 徐婷婷, 鍾婷婷, 陳瑞克, 關玉偉, 陳偉*.(2014)大蒜素通過抑制細胞內活性氧的產生來保護大鼠心肌母細胞(H9c2細胞)免受過氧化氫誘導的氧化損傷。國際食品科學與營養雜誌。65(7): 868-873.
  • 李瑞沃斯, 楊 C, 薛 ASM, 關耀偉, 李思明, 海美明, 陳偉偉, 豪斯曼 M, 范豪特 PM, 梁家輝.(2014) 麥角硫因在人內皮細胞中的攝取和保護作用。藥理學和實驗治療學雜誌。350(3): 691-700.
  • 吳永峰, 鄧平, 岑德, 林偉文, 莫丹強, 陳偉*.(2014)精液黃芪:民族藥理學,植物化學和藥理學評論。民族藥理學雜誌。155(1): 39-53.
  • 岑天嵐, 陳婷婷, 王玉華, 楊建軍, 莫大偉, 陳偉*.(2014) 具有高脂血症作用的中藥材及配方研究進展.國際生物醫學研究。2014:925302.
  • 李文瑩, 吳玉芳, 張華, 郭志東, 郭DJ, 關耀偉, 梁家輝, 李思明, 於平, 陳偉*.(2014) 大黃素通過誘導細胞凋亡引起人肺腺癌A549細胞的細胞毒性。炎症藥理學。22(2):127-134.
  • 李瑞文, 楊春, 關耀偉, 陳偉文, 李明文, 梁國強.(2013) 有機陽離子轉運蛋白-3和質膜單胺轉運蛋白參與人腦血管平滑肌細胞4-羥色胺攝取.藥理學前沿。14:<>.
  • 張華, 李春, 郭新, 張慶偉, 陳偉*.(2013)虎杖幹根及其成分的藥理作用研究進展.循證補充和替代醫學。2013: 208349.
  • 陳桂華, 羅畢克化學, 朱建特, 岳國強, 姜忠, 劉華, 黃茹, 陳偉偉, 岳碧克, 黃RNS, (2013) 人參提取物通過改變甘油三酯代謝和下調動脈粥樣硬化相關基因來恢復高葡萄糖誘導的血管功能障礙。循證補充和替代醫學。2013: 797310.
  • 瀨戶SW, 區兆倫, 潘CC, 張琪, 李瑞文, 楊振華, 孔SK, 魏思敏, 萬善, 何慧, 李文德, 海議員, 陳偉*, 梁國強, 關耀.(2013)急性辛伐他汀抑制豬冠狀動脈肌細胞的K ATP通道。公共圖書館一號。8(6):e66404。
  • Ng YF, Wong, SL, Cheng HL, Yu PHF, Chan SW*. (2013) The microbiological quality of ready-to-eat food in Siu Mei and Lo Mei shops in Hong Kong. Food Control. 34: 547-553.
  • Sham TT, Yuen ACY, Ng, YF, Chan CO, Mok DKW, Chan SW*. (2013) A Review of the Phytochemistry and Pharmacological Activities of Raphani Semen. Evidence-Based Complementary and Alternative Medicine. 2013: 636194.
  • Kwok CY, Li C, Cheng HL, Ng YF, Chan TY, Kwan YW, Leung GPH, Lee SMY, Mok DKW, Yu PHF, Chan SW*. (2013) Cholesterol Lowering and Vascular Protective Effects of Ethanolic Extract of Dried Fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in Diet-induced Hypercholesterolaemic Rat Model. Journal of Functional Foods. 5: 1326-1335.
  • Li CM, Wu JH, Yang RF, Dong XL, He ZY, Tian XL, Guo DJ, Wong MS, Qiu TQ, Chan SW*. (2013) Ligusticum chuanxiong Prevents Ovariectomy-Induced Liver and Vascular Damages in Rats.  American Journal of Chinese Medicine. 41(4): 831-848.
  • Wu JH, Leung GPH, Kwan YW, Sham TT, Tang JY, Wang YH, Wan JB, Lee SMY, Chan SW*. (2013) Suppression of Diet-Induced Hypercholesterolaemia by Saponins from Panax notoginseng in Rats. Journal of Functional Foods. 5: 1159-1169.
  • Li WY, Chan RYK, Yu PHF, Chan SW*. (2013) Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes. Pharmaceutical Biology. 51(9): 1175-1181.
  • Li F, Wu JH, Wang QH, Shu YL, Wan CW, Chan CO, Mok DKW, Chan SW*. (2013) Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes. Food & Function. 4: 745-753.
  • Chan JYY, Yuen ACY, Chan RYK, Chan SW*. (2013) A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin. Phytotherapy Research. 27: 637-646.
  • Zhang H, Wu MY, Guo DJ, Wan CW, Lau CC, Chan CO, Mok DKW, Chan SW*. (2013) Gui-ling-gao (turtle jelly), a traditional Chinese functional food, exerts anti-inflammatory effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice. Journal of Functional Foods. 5: 625-632
  • Wan CW, Wong CNY, Pin WK, Wong MHY, Kwok CY, Chan RYK, Yu PHF, Chan SW*. (2013) Chlorogenic Acid Exhibits Cholesterol Lowering and Fatty Liver Attenuating Properties by Upregulating the Gene Expression of PPAR-a in Hypercholesterolemic Rats Induced with a High-Cholesterol Diet. Phytotherapy Research. 27: 545-551.
  • Li CM, Dong XL, Fan XD, Wu JH, Wang QH, Tian XL, Guo DJ, Wong MS, Qiu TQ, Chan SW* (2013) Aqueous Extract of Danshen (Salvia Miltiorrhiza Bunge) Protects Ovariectomized Rats Fed with High-fat Diet from Endothelial Dysfunction. Menopause. 20(1):100-109.
  • Guo DJ, Li F, Yu PHF, Chan SW*. (2013) Neuroprotective effects of luteolin against apoptosis induced by 6-hydroxy dopamine on rat pheochromocytoma PC12 cells. Pharmaceutical Biology.   51(2):190-196.
  • Chan SH, Chui CH, Chan SW, Kok SHL, Chan D, Tsoi MYT, Leung PHM, Lam AFY, Chan ASC, Lam KH, Tang JCO. (2013) Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor Agents. ACS Medicinal Chemistry Letter. 4: 170-174.
  • Wu JH, Wang QH, Li F, Shu YL, Chan CO, Mok DKW, Chan SW*. (2012) Suppression of Diet-Induced Hypercholesterolemia by Turtle Jelly, a Traditional Chinese Functional Food, in Rats. Evidence-Based Complementary and Alternative Medicine. 2012:320304
  • Zhou X, Chan SW, Tseng HL, Deng Y, Hoi PM, Choi PS, Or PM, Yang JM, Lam FF, Lee SM, Leung GP, Kong SK, Ho HP, Kwan YW, Yeung JH. (2012) Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions. Phytomedicine. 19(14):1263-1269.
  • Chan E, Chan JYY, Wu JH, Wan CW, Leung GPH, Lee SMY, Kwan YW, Chan SW*. (2012) Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats. Clinical and Experimental Pharmacology and Physiology. 39(10): 894-896.
  • Chan SW*. (2012) Panax ginseng, Rhodiola rosea and Schisandra chinensis. International Journal of Food Sciences and Nutrition. 63 S1:75-81.
  • Kam TS, Wong CY, Kwan PL, Fat-Yiu W, Chiu SM, Chan SW, Yuen KS, Chan R. (2012) Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats. Journal of Medicinal Food. 15(2):190-199.
  • Zhang Y,  Hu G, Li S, Li ZH, Lam CO, Hong SJ, Kwan YW, Chan SW, Leung GP, Lee SM (2012) Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo. Molecular Medicine Reports. 5(3):805-811.
  • Tang WM, Chan E, Kwok CY, Lee YK, Wu JH, Wan CW, Chan RY, Yu PH, Chan SW*. (2012) A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit. Inflammopharmacology. 20(6):307-314.
  • Hu G, Siu SO, Li S, Chu IK, Kwan YW, Chan SW, Leung GP, Yan R, Lee SM (2012). Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae. Xenobiotica. 42(3):294-303.
  • Chan JY, Chan E, Chan SW*, Sze SY, Chan MF, Tsui SH, Leung KY, Chan RY, Chung IY. (2011) Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications. Pharmaceutical Biology. 49(11): 1114-1120.
  • Li S, Lou S, Lei BUW,  Chan TF, Kwan YW, Chan SW, Leung GPH, Tsui SKW, Lee SMY. (2011) Transcriptional Profiling of Angiogenesis Activities of Calycosin in Zebrafish. Molecular BioSystems. 7(11):3112-3121.
  • Yiu WF, Kwan PL, Wong CY, Kam TS, Chiu SM, Chan SW, Chan R. (2011) Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase. Journal of Food Sciences. 76(3):H80-H89.
  • Chan E, Liu XX, Guo DJ, Kwan YW, Leung GP, Lee SM, Chan SW*. (2011) Extract of Scutellaria baicalensis Georgi Root Exerts Protection Against Myocardial Ischemia-Reperfusion Injury in Rats. American Journal of Chinese Medicine. 39(4):693-704.
  • Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW*. (2011) A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 19(5):245-254.
  • Wang N, Wan JB, Chan SW, Deng YH, Yu N, Zhang QW, Wang YT, Lee SM. (2011) Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion. Chinese Medicine. 13;6:37.
  • Wan CW, Lee YK, Kwok CY, Chan RYK, Yu PHF, Chan SW*. (2010) A validated HPLC method with dual wavelength detection on chlorogenic acid and internal standard in plasma and its application in pharmacokinetic study in rats. Journal of Liquid Chromatography & Related Technologies. 33:324-335.
  • Alex D, Leong EC, Zhang ZJ, Yan GTH, Cheng SH, Leong CW, Li ZH, Lam KH, Chan SW, Lee SMY. (2010) Resveratrol derivative, trans-3,5,4’-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2/KDR and cell-cycle modulation. Journal of Cellular Biochemistry. 109:339-346.
  • Wu JH, Li Q, Wu MY, Guo DJ, Chen HL, Chen SL, Seto SW, Au ALS, Poon CCW, Leung GPH, Lee SMY, Kwan YW, Chan SW* (2010) Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. Journal of Nutritional Biochemistry. 21(7):613-620.
  • Seto SW, Lam TY, Or PMY, Lee WYW, Au ALS, Poon CCW, Chan SW, Yeung JHK, Leung GPH, Lee SMY, Ngai SM, Kwan YW. (2010) Folic acid consumption reduces resistin level and restores the blunted acetylcholine-induced aortic relaxation in obese/diabetic mice. Journal of Nutritional Biochemistry. 21(9):872-880.
  • Chan E, Wong CYK, Wan CW, Kwok CY, Wu JH, Ng KM, So CH, Au ALS, Poon CCW, Seto SW, Kwan YW, Yu PHF, Chan SW*. (2010) Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer. American Journal of Chinese Medicine. 38(4):815-827.
  • Kwok CY, Wong CNY, Yau, MYC, Yu PHF, Au ALS, Poon CCW, Seto SW, Lam TY, Kwan YW, Chan SW*. (2010) Consumption of dried fruit of Crataegus pinnatifida (hawthorn) suppresses high cholesterol diet-induced hypercholesterolemia in rats. Journal of Functional Foods. 2(3):179-186.
  • Yang C, Kwan YW, Au AL, Poon CC, Zhang Q, Chan SW, Lee SM, Leung GP. (2010) 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery. Prostaglandins and Other Lipid Mediators. 93(1-2):44-51.
  • Tang JY, Li S, Li ZH, Zhang ZJ, Hu G, Cheang LC, Alex D, Hoi MP, Kwan YW, Chan SW, Leung GP, Lee SM. (2010) Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC. PLoS One. 5(7):e11822.
  • Yang C, Kwan YW, Chan SW, Lee SM, Leung GP. (2010) Potentiation of EDHF-mediated relaxation by chloride channel blockers. Acta Pharmacologica Sinica. 31(10):1303-1311.
  • Poon CC, Seto SW, Au AL, Zhang Q, Li RW, Lee WY, Leung GP, Kong SK, Yeung JH, Ngai SM, Ho HP, Lee SM, Chan SW, Kwan YW. (2010) Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery. British Journal of Pharmacology. 161(5):1086-1098.
  • Meng Z, Chen SL, Seto SW, Kwan YW, Chan SW*. (2009) Correlation of Anti-oxidative property and Vaso-relaxation Effect of Major Active Constituents of Traditional Chinese Medicine. Pharmaceutical Biology. 47:366-371.
  • Seto SW, Lam TY, Tam HL, Au ALS, Chan SW, Wu JH, Yu PHF, Leung GPH, Ngai SM, Yeung JHK, Leung PS, Lee SMY, Kwan YW. (2009) Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice. Phytomedicine. 16:426-436.
  • Seto SW, Lau WS, Lam HY, Au ALS, Chim SSC, Ngai SM, Chan SW, Leung DTN, Kwan YW. (2009) Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery. European Journal of Pharmacology. 605:129-137.
  • Yan LP, Zhuang YL, Chan SW, Chen SL, Shi GG. (2009) Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta. Naunyn Schmiedebergs Arch Pharmacology. 379:587-597.
  • Li RWS, Seto SW, Au ALS, Kwan YW, Chan SW, Lee SMY, Tse CM, Leung GPH. (2009) Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells. European Journal of Pharmacology. 612:15-20.
  • Li WY, Chan SW*, Guo DJ, Chung MK, Leung TY, Yu PHF. (2009) Water extract of Rheum officinale Baill. induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. Journal of Ethnopharmacology. 124:251-256.
  • Li Q, Wu JH, Guo DJ, Cheng HL, Chen SL, Chan SW*. (2009) Suppression of diet-induced hypercholesterolemic atherosclerosis by scutellarin in rats. Planta Medica. 75:1203-1208.
  • Lam TY, Seto SW, Au ALS, Poon CCW, Lam HY, Lau MW, Chan SW, Ngai SM, Leung GPH, Lee, SMY, Tsui SKY, Kwan YW. (2009) Folic Acid Supplementation Modifies b-Adrenoceptor-Mediated in vitro Lipolysis of Obese/Diabetic (+db/+db) Mice. Experimental Biology and Medicine. 16:426-436.
  • Chan SW, Li S, Kwok CY, Benzie IFF, Szeto YT, Guo DJ. He XP, Yu PHF. (2008) Studies on the Antioxidant Activity of Chinese Medicinal Herbs. Pharmaceutical Biology. 48:587-595.
  • Guo DJ, Cheng HL, Chan SW, Yu PHF. (2008) Antioxidant activity and the total phenolic content of tonic Chinese Medicinal Herbs. Inflammopharmacology. 16: 1-7.
  • Chen C, Cheng YC, Yu CH, Chan SW, Cheung MK, Yu PHF. (2008) In vitro cytotoxicity, hemolysis assay, and biodegradation behavior of biodegradable poly(3-hydroxybutyrate)-poly(ethylene glycol)-poly(3-hydroxybutyrate) nanoparticles as potential drug carriers. Journal of Biomedical Materials Research. Part A. 87:290-298.
  • Seto SW, Lam TY, Leung GPH, Au ALS, Ngai SM, Chan SW, Kwan YW. (2007) Comparison of vascular relaxation, lipolysis and glucose uptake by peroxisome proliferator-activator receptor-g activation in +db/+m and +db/+db mice. European Journal of Pharmacology. 572:40-48.
  • Hao XN, Chan SW*, Chen SL. (2007) Detection of puerarin and danshensu in traditional Chinese medicinal preparation containing Pueraria lobata and Salvia miltiorrhiza by high-performance liquid chromatography. Journal of Liquid Chromatography and Related Technologies. 30:2779-2787.
  • Chan SW, Rudd JA, Lin G, Li P. (2007) Action of anti-tussive drugs on the emetic reflex of Suncus murinus (House Musk Shrew). European Journal of Pharmacology. 559:196-201.
  • Li WY, Chan SW*, Yu PHF, Guo DJ. (2007) Correlation between antioxidative power and anticancer activity in herbs from traditional Chinese medicine formulae with anticancer therapeutic effect. Pharmaceutical Biology. 45:541-546.
  • Seto SW, Au ALS, Lam TY, Chim SSC, Lee SMY, Wan S, Tjiu DCS, Shigemura N, Yim APC, Chan SW, Tsui SKW, Leung GPH, Kwan YW. (2007) Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K channels of porcine coronary artery smooth muscle cells. British Journal of Pharmacology. 151:987-997.+
  • Yan LP, Chan SW*, Chan ASC, Chen SL, Ma XJ, Xu HX. (2006) Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. Life Sciences. 79:324-330.
  • Li SL, Lin G, Chan SW, Li P. (2001) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high performance liquid chromatography coupled with evaporative light scattering detector. Journal of Chromatography A. 909:207-214.
  • Sum TSW, Chan SW, Rudd JA, Yeung JHK. (2001) Actions of glucocorticoids to antagonise cisplatin-induced acute and delayed emesis in ferret. European Journal of Pharmacology. 417:231-237.
  • Lin G, Li P Li SL, Chan SW. (2001) Chromatographic analysis of Fritillaria isosteroidal alkaloids, the active principles of the most commonly used antitussive traditional Chinese medicine Beimu. Journal of Chromatography A. 935:321-338.
  • Li SL, Li P, Lin G, Chan SW, Ho YP. (2000) Simultaneous determination of seven major isosteroidal alkaloids in bulbs of Fritillaria by gas chromatography. Journal of Chromatography A. 873:221-228.
  • Chan SW, Li SL, Lin G, Li P. (2000) Pharmacokinetic study and determination of imperialine, the major bioactive component in antitussive Fritillaria cirrhosa, in rat by high-performance liquid chromatography coupled with evaporative light scattering detector. Analytical Biochemistry. 285:172-175.
  • Li SL, Chan SW, Li P, Lin G, Zhou GH, Ren YJ, Chiu FCK. (1999) Pre-column derivatization and gas chromatographic determination of alkaloids in bulbs of Fritillaria. Journal of Chromatography A. 859:183-192.

 

*As corresponding author